Semaglutide
GLP-1 Receptor AgonistBrand: Ozempic
Method: Weekly injection
Semaglutide is a GLP-1 receptor agonist that works by mimicking the hormone GLP-1, which targets areas of the brain that regulate appetite and food intake. It helps you feel fuller longer, reduces cravings, and slows gastric emptying.
- Internationally approved for chronic weight management
- Once-weekly subcutaneous injection
- Clinically proven in large-scale trials
- Gradual dose escalation over 16-20 weeks
- Works best combined with lifestyle changes
Average weight loss
Up to 15% body weight
Results vary by individual
Tirzepatide
GLP-1/GIP Dual AgonistBrand: Mounjaro
Method: Weekly injection
Tirzepatide is a first-in-class dual GIP and GLP-1 receptor agonist. It targets two incretin hormones simultaneously, providing enhanced blood sugar control and significant weight loss effects. Clinical trials have shown it to be one of the most effective weight loss medications available.
- Dual-action mechanism (GLP-1 + GIP)
- Once-weekly subcutaneous injection
- Shown to be more effective than semaglutide in head-to-head trials
- Internationally approved for type 2 diabetes and weight management
- Dose escalation over 20+ weeks
Average weight loss
Up to 22% body weight
Results vary by individual
Liraglutide
GLP-1 Receptor AgonistBrand: Saxenda / Victoza
Method: Daily injection
Liraglutide is a GLP-1 receptor agonist that mimics the natural hormone GLP-1, reducing appetite and food intake. Saxenda is specifically approved for weight management, while Victoza is used for diabetes. Both are widely available across Egyptian pharmacies.
- Specifically approved for weight management (Saxenda)
- Once-daily subcutaneous injection
- Widely available in Egyptian pharmacies
- Gradual dose escalation over 4-5 weeks
- Well-established safety profile with years of use
Average weight loss
Up to 8% body weight
Results vary by individual
Metformin
BiguanideBrand: Glucophage
Method: Daily tablet
Metformin is a well-established medication primarily used for type 2 diabetes that also supports weight management. It works by reducing glucose production in the liver, improving insulin sensitivity, and may modestly reduce appetite.
- Decades of safety data
- Oral tablet taken 1-2 times daily
- May be combined with GLP-1 medications
- Very affordable generic medication
- Additional cardiovascular benefits
Average weight loss
Up to 5% body weight
Results vary by individual
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